Biochemical Markers for Huntington's Chorea
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چکیده
منابع مشابه
Biochemical Markers for Huntington's Chorea
The uptake of dopamine (DA) by platelet rich plasma was assayed in II patients with Huntington's chorea (H. C). The results confirmed the previous observation that platelets from H.C. patients take up, at equilibrium, more dopamine than do platelets from normal control subjects. The mean difference was 50% higher at DA substrate concentrations of 0.11 mM. However, attempts to confirm the higher...
متن کاملBiochemical markers for Huntington's chorea.
The uptake of dopamine (DA) by platelet rich plasma was assayed in 11 patients with Huntington's chorea (H.C.). The results confirmed the previous observation that platelets from H.C. patients take up, at equilibrium, more dopamine than do platelets from normal control subjects. The mean difference was 50% higher at DA substrate concentrations of 0.11 mM. However, attempts to confirm the higher...
متن کامل[Biochemical aspects of Huntington's chorea].
Fifteen patients affected by Huntington's chorea were divided into two groups, 'slow' and 'fast', according to IQ scores on the Wechsler-Bellevue scale, and scores on some motor performance tests. A possible correlation was looked for between some biochemical data (cerebrospinal fluid (CSF), homovanillic acid (HVA), and 5-hydroxyindolacetic acid (5HIAA) levels, plasma dopamine-beta-hydroxylase ...
متن کاملA biochemical study of Huntington's chorea.
It is now generally accepted that Huntington's chorea is inherited through a single dominant autosomal gene but apart from this little is known of the aetiology. Earlier investigators had implicated endocrine factors (Mulon and Porak, 1912; Bize, 1934) but without very convincing evidence. With the advent ofnew drugs that had profound effects on the nervous system the idea of a neuronal basis f...
متن کاملThe Search for Biochemical Markers
Scientists are searching for biochemical markers for alcoholism that would allow researchers to distinguish easily and reliably between alcoholics and nonalcoholics or between people at risk for alcoholism and those not at risk. Two proposed markers that have been studied intensively are the activity levels of the enzymes platelet monoamine oxidase (MAO) and platelet adenylyl cyclase (AC). Leve...
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ژورنال
عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
سال: 1980
ISSN: 0317-1671,2057-0155
DOI: 10.1017/s0317167100022745